Vitamin C and E reduce pelvic painThe Effect of Combined Vitamin C and Vitamin E Supplementation on Oxidative Stress Markers in Women with Endometriosis: A Randomized, Triple-Blind Placebo-Controlled Clinical Trial.
Significant positive health impact
We examined the effects of vitamin C and E on pelvic pain in women with endometriosis through a triple-blind, placebo-controlled trial. Sixty women aged 15-45 participated, receiving either the vitamin combination or a placebo daily for eight weeks.
Our results revealed noteworthy decreases in pelvic pain, dysmenorrhea, and dyspareunia for those who took vitamins, supporting their potential in managing endometriosis symptoms. While oxidative stress markers showed changes, total antioxidant capacity did not significantly decline.
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We investigated whether vitamin E could help with primary dysmenorrhea, a common cause of pelvic pain for young women. In our study, 278 girls aged 15-17 took either vitamin E or a placebo before and during their menstrual periods.
Results showed that those taking vitamin E experienced significantly less pain and shorter pain duration compared to the placebo group. There was also a notable reduction in menstrual blood loss. This suggests that vitamin E may be a beneficial option for managing menstrual discomfort.
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We examined the potential of a multimodal therapy approach for treating chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) using the UPOINTS phenotyping system. Involving 914 patients, the study combined α-blockers, supplements like selenium, and antibacterial agents among others.
After a six-month course, we noted significant improvements in symptoms, with 77.5% of patients achieving a meaningful reduction in their pain scores. Notably, patients with the inflammatory subtype showed marked symptom relief compared to the non-inflammatory group. This suggests a tailored approach could effectively address the complexities of CP/CPPS.
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Selenium enhances pelvic pain treatmentTreatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus selenium and lycopene (Profluss) versus S. repens alone: an Italian randomized multicenter-controlled study.
High relevance for treatment modalities
We evaluated the effects of a treatment combining Serenoa repens with selenium and lycopene, known as Profluss, against Serenoa repens alone for chronic pelvic pain in 102 men. After an 8-week period, both groups experienced symptom improvements. However, the Profluss group showed a significantly greater reduction in pelvic pain scores and additional benefits in other measures, suggesting that selenium can enhance treatment effectiveness for this condition.
While both treatments offered relief, Profluss was particularly beneficial. This finding indicates that adding selenium to standard therapy might be advantageous in managing pelvic pain.
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Vitamin E supports pelvic pain reliefVitamin C and E antioxidant supplementation may significantly reduce pain symptoms in endometriosis: A systematic review and meta-analysis of randomized controlled trials.
High relevance for pain management
We explored the impact of antioxidants, specifically vitamins C and E, on pelvic pain associated with endometriosis. Analyzing data from five randomized controlled trials, we found that patients receiving vitamin supplementation reported significant reductions in chronic pelvic pain, dysmenorrhea, and dyspareunia compared to those on placebo.
This suggests that these vitamins may play a beneficial role in alleviating symptoms for those suffering from endometriosis-related pain. Overall, antioxidant supplementation presents a promising avenue for management of this challenging condition.
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